Health

From a lecture in March, 1998 at the National Institutes of Health, Dr. Leshner explained how brain function is modified by drug use and how that change persists after an individual stops taking drugs. Addiction also has to be recognized as a result of many bio-behavioral factors.Dr. Leshner said a user does not have control over the change when voluntary drug use becomes a compulsive addiction. He likens the change to a flip of a switch, although the change may be a result of opponent processes where changes have accumulated over time. Regardless, Dr. Leshner believes it is important that people understand that once addicted, a person is literally in a different brain state.Anyone that has known and witnessed the changes in behavior and ethics in a person caught in the thralls of addiction can see the declining spiral of personal care and ethics, work ethics, emotional stability and generally, a feeling that one hardly recognizes the addicted person as being the same individual as they were before the drug use.

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One very important point to know is that any drug use may set off these destructive behaviors in an individual and that using drugs “recreationally” is playing Russian Roulette with one’s life. The effects of these “poisons” on the brain and nervous system are always destructive, but the timeline of when the effects will be obvious varies from immediately to, sometimes, after years of “casual” use.The scientist’s say that one of the tasks of treatment is to revert the brain to its original state or repairing the damage that these poisons can do. Some scientist believe that this can be done by introducing other drugs, then called medicines, into the delicate brain chemistry of someone suffering from drug addiction. That is what National Institute of Drug Abuse (NIDA) is doing now as it begins to design new medications. "We have molecular targets," Dr. Leshner said.” We don't need serendipity." Serendipity is defined as “a natural gift for making useful discoveries by accident.”

 


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